By Edward L. Engelhardt (Eds.)
content material: [Beta]-adrenoceptor antagonists as antihypertensive brokers / Richard Clarkson --
Centrally performing antihypertensive brokers / Wolfgang Hoefke --
Antihypertensives appearing through a peripheral mechanism / John E. Francis --
Antihypertensive brokers as visible via the clinician / Gaddo Onesti.
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SJOERDSMA: S c i e n c e 1 9 6 0 , 131, 1 8 9 0 HORWITZ, D . and A . SJOERDSMA: Life Sci. : Circulation Res. 1 9 6 7 , 21 Suppl. , 119 CARLSSON, A . and M . LINDQVIST: A c t a physiol. scand. 7. DAY, M . D . J. RAND: 4. 5. 1962, 54, 87 15, 8. J. Pharm. P h a r m a c o l . , W. LANGENECKERT and P . ; ACS Symposium Series; American Chemical Society: Washington, DC, 1976. 52 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. ANTIHYPERTENSIVE AGENTS Schmiedebergs A r c h .
In "Catapres i n H y p e r t e n s i o n " E d . C O NOLLY, M . E . 23 B u t t e r w o r t h , London, 1970 DAHLSTRÖM, A . and K . FUXE: A c t a physiol. scand. 1964, 62, Supp. 232 DOBA, N . J. REIS: Circulation Res. 1973, 32, 584 DE JONG, W . : E u r o p . J. P h a r m a c o l . : Naunyn-Schmiedebergs A r c h . P h a r m a c o l . , C . A . M. ; ACS Symposium Series; American Chemical Society: Washington, DC, 1976. 2. 32. HOEFKE Centrally Acting Antihypertensive Agents ROBSON, R . D . and H .
Autonomic structures i n the c e n t r a l nervous system. As already mentioned, a l l these structures are linked by one or more c o n t r o l l i n g systems. By influencing one or the other part of these systems the regulation may change in such a way that the blood pressure f a l l s . My lecture p r i m a r i l y deals with substances influencing these auto nomic structures i n the CNS. I should l i k e to t a l k f i r s t about methyldopa (Fig. 4). I t i s well known that a f t e r stimulation of a sympa t h e t i c nerve, noradrenaline i s l i b e r a t e d at the nerve ending.